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What kinds of brain changes can people experience when they take drugs?
Addiction can be defined by the inability for one to stop. Not when it threatens your health. It shouldn't be used to cause financial, emotional, and other problems for yourself or your loved ones. Even if you are determined to quit, your need for drugs may consume you at any hour of day.

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As a person continues to use drugs, the brain adapts by reducing the ability of cells in the reward circuit to respond to it. This reduces the high that the person feels compared to the high they felt when first taking the drug—an effect known as tolerance. They might take more of the drug to try and achieve the same high. These brain adaptations often lead to the person becoming less and less able to derive pleasure from other things they once enjoyed, like food, sex, or social activities.
The Effect on Your Brain This results in you being inspired to do more.

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Biology. About half of the risk for addiction can be attributed to genes. Other mental disorders, gender, ethnicity and race may all play a role in drug abuse and addiction risk.
Environment. The environment a person lives in has many factors. This includes family and friends as well as economic situation and overall quality of living. Peer pressure and early exposure to drugs, stress and parental supervision all can have an important impact on someone's chances of developing a drug addiction.

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Brain changes that are a result over time of drug addiction can pose a challenge to an addict's ability to self-control and hinder their ability resist their overwhelming desire to use drugs. Substance addiction is a serious disease that can lead you to relapse.
Addiction can also be caused by opioids and other narcotic pain medications, which can either be legally obtained through prescriptions or illegally. This problem is now epidemically widespread in the United States. Two-thirds of those who died of a drug overdose in 2018 were caused by opioids.

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To put it another way, if opioids are used to manage pain regularly, you may develop a tolerance or become dependent upon them. This does not necessarily mean you have an addiction. Only a few people are able to become addicted to opioids even though they have been prescribed properly and under the direction of a physician.
Avoid becoming dependent on painkillers. Follow these steps. Let your doctor know if you have ever been a victim to drug abuse or addiction. They will be able to prescribe the medication that is most effective for your needs.

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Biology. Around 50% of an individual's risk for addiction is determined by the genes they inherit from their parents. Other factors that can increase the likelihood of addiction and drug use include gender, ethnicity, and presence of mental illness.
Remember, it’s common for people to develop a tolerance to pain medication and to need higher doses to get the same level of pain relief. This is normal and is not a sign of addiction. With addiction, you may need to utilise bigger amounts, but it’s not for pain relief. Still, talk to your doctor if this effect becomes troubling.

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How to Prevent Addiction to Prescribed Painkillers. Most people who take their pain medicine as directed by their doctor do not become addicted, even if they take the medicine for a long time. Fears about addiction should not prevent you from using narcotics to relieve your pain. But if you’ve abused drugs or alcohol in the past or have family members who have, you may be at a higher risk.
The Effect on Your Mental Health: Your brain is programmed to crave comparable events that result in a favourable emotional state. To motivate you to carry out these behaviours again and again.